Comprehensive Physiology Wiley Online Library

Human Nervous System

Full Article on Wiley Online Library



Abstract

The sections in this article are:

1 Heterogeneity of Aging of the Nervous System: Genius and Dementia in the Ninth Decade
2 Changes in the Nervous System Associated with Normal Aging
2.1 An Important Caveat: Are Changes due to Differences between Generations or to Aging?
2.2 Evidence That Semantic Knowledge Is Retained Late into the Life Span
2.3 Evidence That We Become Slower as We Age
2.4 Loss of Episodic and Working Memory Is a Common but Not Inevitable Accompaniment of Aging
2.5 How Much Does Perception Change with Age?
2.6 Cerebral Blood Flow and Cerebral Metabolism in Aging
2.7 Gait and Motor Changes in the Elderly
2.8 Biological Bases of Changes in Cognition and Gait during Normal Aging
2.9 Role of Extrapyramidal Changes
3 Alzheimer's Disease
3.1 Dementing Illnesses
3.2 Neuropathology of Alzheimer's Disease
3.3 Molecular Changes in Alzheimer's Disease
3.4 Molecular Genetics of Alzheimer's Disease
3.5 Epidemiological Findings Strengthen the Concept of Alzheimer's Disease as a Chronic Disease
4 What can be Done to Accelerate Research into Normal Aging?
4.1 Overlap of Alzheimer's Disease and Normal Aging Research
4.2 Need for a New Infrastructure for Normal Aging Research
Figure 1. Figure 1.

Alzheimer's disease as a chronic disease.

Modified from Fig. 4 in Katzman and Kawas


Figure 1.

Alzheimer's disease as a chronic disease.

Modified from Fig. 4 in Katzman and Kawas
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Robert Katzman. Human Nervous System. Compr Physiol 2011, Supplement 28: Handbook of Physiology, Aging: 325-344. First published in print 1995. doi: 10.1002/cphy.cp110112