Comprehensive Physiology Wiley Online Library

Pharmacology of neuroendocrine peptides

Full Article on Wiley Online Library



Abstract

The sections in this article are:

1 Gastrin and Cholecystokinin (CCK)
1.1 Classification of Gastrin‐CCK Receptors
1.2 Locus of Receptors
1.3 Modulation of Gastrin‐CCK Receptors
1.4 Postreceptor Mechanisms
1.5 Applied Pharmacology in the Gut
2 Substance P and Tachykinins
2.1 Receptors to Tachykinins
2.2 Degradation of Tachykinins
2.3 Actions of Tachykinins
3 Vasoactive Intestinal Polypeptide (VIP)
3.1 Receptors
3.2 Antagonists
3.3 Control of Motility
4 Opiates
4.1 Natural Opiates
4.2 Receptor Types
4.3 Degradation of Opiates
4.4 Opiates and Guinea Pig Ileum
4.5 Actions on Segments of Gastrointestinal Tract in other Species
4.6 Opiates, Immune System, and Gastrointestinal Motility
4.7 Rational Design of Drugs
5 Other Peptides
5.1 Motilin
5.2 Somatostatin
5.3 Neurotensin
5.4 Gastrin‐Releasing Polypeptide/Bombesin Family
5.5 Galanin
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Edwin E. Daniel, Stephen M. Collins, Jo‐Ann E. T. Fox, Jan D. Huizinga. Pharmacology of neuroendocrine peptides. Compr Physiol 2011, Supplement 16: Handbook of Physiology, The Gastrointestinal System, Motility and Circulation: 759-816. First published in print 1989. doi: 10.1002/cphy.cp060120