Comprehensive Physiology Wiley Online Library

Salivary Mucin Secretion

Full Article on Wiley Online Library



Abstract

The sections in this article are:

1 Hemical Composition and Structure of Salivary Mucins
2 Physiological Alteration of Mucin Structure
3 Biosynthesis of Mucins
4 Submandibular Gland
4.1 Submandibular Mucin Secretion
4.2 Membrane Receptors and Their Role in Mucin Secretion
4.3 Other Possible Effectors of Mucin Secretion
4.4 Signal Transduction
4.5 Cellular Mediators of Mucin Secretion
4.6 Importance of Calcium in Submandibular Mucin Secretion
4.7 Summary
5 Sublingual Gland
6 Minor Salivary Glands
7 Addendum
Figure 1. Figure 1.

Time course of effect of β‐adrenergic receptor stimulation on rat submandibular cellular cAMP levels, on cellular cAMP‐dependent protein kinase activity, and on endogenous protein phosphorylation of 2 β‐adrenergic‐dependent, integral membrane phosphoproteins.

Adapted from Quissell et al. 90,91,93
Figure 2. Figure 2.

Concentration dependence of isoproterenol stimulation on mucin secretion, cellular cAMP‐dependent protein kinase activation, and on endogenous protein phosphorylation of 2 integral membrane phosphoproteins.

Adapted from Quissell et al. 89,90,93
Figure 3. Figure 3.

Summary of cellular molecular events that appear to be involved during rat submandibular mucin secretion.

Adapted from Quissell et al. 90–93


Figure 1.

Time course of effect of β‐adrenergic receptor stimulation on rat submandibular cellular cAMP levels, on cellular cAMP‐dependent protein kinase activity, and on endogenous protein phosphorylation of 2 β‐adrenergic‐dependent, integral membrane phosphoproteins.

Adapted from Quissell et al. 90,91,93


Figure 2.

Concentration dependence of isoproterenol stimulation on mucin secretion, cellular cAMP‐dependent protein kinase activation, and on endogenous protein phosphorylation of 2 integral membrane phosphoproteins.

Adapted from Quissell et al. 89,90,93


Figure 3.

Summary of cellular molecular events that appear to be involved during rat submandibular mucin secretion.

Adapted from Quissell et al. 90–93
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David O. Quissell, Lawrence A. Tabak. Salivary Mucin Secretion. Compr Physiol 2011, Supplement 18: Handbook of Physiology, The Gastrointestinal System, Salivary, Gastric, Pancreatic, and Hepatobiliary Secretion: 79-91. First published in print 1989. doi: 10.1002/cphy.cp060305