Comprehensive Physiology Wiley Online Library

Synthesis, Internalization, Recycling, and Regulation of Peptide Hormone Receptors

Full Article on Wiley Online Library



Abstract

The sections in this article are:

1 Classification of Peptide Receptors
2 Overview of Regulatory Mechanisms
3 Receptor Biosynthesis
4 Endocytotic Cycle
5 Receptor Sequestration
5.1 Sequestration Motifs and Domains
6 Receptor Regulation
7 Conclusions
Figure 1. Figure 1.

Schematic showing the major domains of various structurally distinct peptide receptors.

Figure 2. Figure 2.

Cartoon showing the clathrin‐coated pit mediated endocytotic cycle.



Figure 1.

Schematic showing the major domains of various structurally distinct peptide receptors.



Figure 2.

Cartoon showing the clathrin‐coated pit mediated endocytotic cycle.

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Stuart C. Sealfon. Synthesis, Internalization, Recycling, and Regulation of Peptide Hormone Receptors. Compr Physiol 2011, Supplement 20: Handbook of Physiology, The Endocrine System, Cellular Endocrinology: 23-38. First published in print 1998. doi: 10.1002/cphy.cp070102