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Tubuloglomerular Feedback Control of Renal Vascular Resistance

Jürgen Schnermann, Dieter A. Häberle, John M. Davis, Klaus Thurau

10.1002/cphy.cp080234

Source: Supplement 25: Handbook of Physiology, Renal Physiology

Originally published: 1992

Published online: January 2011

Full Article on Wiley Online Library



Abstract

The sections in this article are:

1 Historical Background
2 TGF Response Characteristics
2.1 Open‐Loop Studies
2.2 Closed‐Loop Studies
3 Mechanisms of the TGF Reaction
3.1 Anatomical Pathway
3.2 Luminal Signal
3.3 Stimulus–Response Coupling Mechanisms
3.4 The Vascular Reaction
4 Integrative Feedback Function
4.1 Mechanisms of TGF Resetting
4.2 Phenomenology of TGF Responsiveness
Figure 1. Figure 1.

Summary of open‐loop feedback studies determining effect of changes in end‐proximal flow rate (VLP) on single nephron filtration rate (SNGFR). Numbers refer to reference list.
Figure 2. Figure 2.

Nonlinear relationship between loop of Henle perfusion rate (VLP) and single nephron filtration rate (SNGFR) in a study in which multiple determinations of GFR were made in the same nephron.

From ref. 42
Figure 3. Figure 3.

Schematic diagram illustrating definitions used to describe characteristics of tubuloglomerular feedback response.
Figure 4. Figure 4.

Results from retrograde perfusion studies showing relationship between perfusate NaCl concentration and early proximal flow rate (VEP). Equation derived from data in ref. 252. Superimposed data indicate measurements of stop‐flow pressure (PSF) changes in response to retrograde perfusion [triangles, refs. 14,15; open circles, ref. 268; closed circles, ref. 266]. Numerical identity of VEP and PSF changes is accidental.
Figure 5. Figure 5.

Summary of open‐loop feedback studies determining effect of changes in loop perfusion rate (VLP) on stop‐flow pressure (PSF). Source of results is indicated by numbers from reference list.
Figure 6. Figure 6.

Schematic diagram showing direct relationship between SNGFR and the TGF signal (solid line in center diagram) and inverse relationship between TGF signal and SNGFR (broken line in center diagram). Alterations in resistance can be achieved by modifications in transport altering the relationship between SNGFR and TGF signal (dashed lines in right‐hand insert; note that convention of plotting the dependent variable on the ordinate is not followed), by modifications in effect of TGF signal on SNGFR (dashed lines in left‐hand insert), or by perturbations extrinsic to feedback system.
Figure 7. Figure 7.

Effect of loop perfusion rate on pressure dependency of SNGFR or stop‐flow pressure. Left‐hand diagram shows effect of arterial pressure on SNGFR without loop perfusion (SNGFRprox, loop perfusion rate 0 nl/min), during loop perfusion at 40 nl/min, and on distal SNGFR. Right‐hand diagram shows measurements of stop‐flow pressure performed under similar conditions.

from ref. 105. from ref. 237


Figure 1.

Summary of open‐loop feedback studies determining effect of changes in end‐proximal flow rate (VLP) on single nephron filtration rate (SNGFR). Numbers refer to reference list.



Figure 2.

Nonlinear relationship between loop of Henle perfusion rate (VLP) and single nephron filtration rate (SNGFR) in a study in which multiple determinations of GFR were made in the same nephron.

From ref. 42


Figure 3.

Schematic diagram illustrating definitions used to describe characteristics of tubuloglomerular feedback response.



Figure 4.

Results from retrograde perfusion studies showing relationship between perfusate NaCl concentration and early proximal flow rate (VEP). Equation derived from data in ref. 252. Superimposed data indicate measurements of stop‐flow pressure (PSF) changes in response to retrograde perfusion [triangles, refs. 14,15; open circles, ref. 268; closed circles, ref. 266]. Numerical identity of VEP and PSF changes is accidental.



Figure 5.

Summary of open‐loop feedback studies determining effect of changes in loop perfusion rate (VLP) on stop‐flow pressure (PSF). Source of results is indicated by numbers from reference list.



Figure 6.

Schematic diagram showing direct relationship between SNGFR and the TGF signal (solid line in center diagram) and inverse relationship between TGF signal and SNGFR (broken line in center diagram). Alterations in resistance can be achieved by modifications in transport altering the relationship between SNGFR and TGF signal (dashed lines in right‐hand insert; note that convention of plotting the dependent variable on the ordinate is not followed), by modifications in effect of TGF signal on SNGFR (dashed lines in left‐hand insert), or by perturbations extrinsic to feedback system.



Figure 7.

Effect of loop perfusion rate on pressure dependency of SNGFR or stop‐flow pressure. Left‐hand diagram shows effect of arterial pressure on SNGFR without loop perfusion (SNGFRprox, loop perfusion rate 0 nl/min), during loop perfusion at 40 nl/min, and on distal SNGFR. Right‐hand diagram shows measurements of stop‐flow pressure performed under similar conditions.

from ref. 105. from ref. 237
References
 1. Arend, L. J., C. I. Thompson, M. A. Brandt, and W. S. Spielman. Elevation of intrarenal adenosine by maleic acid decreases GFR and renin release. Kidney Int. 30: 656–661, 1986.
 2. Arendshorst, W. J. Altered reactivity of tubuloglomerular feedback. Annu. Rev. Physiol. 49: 295–317, 1987.
 3. Arendshorst, W. J., W. F. Finn, and C. W. Gottschalk. Nephron stop‐flow pressure response to obstruction for 24 hours in the rat kidney. J. Clin. Invest. 53: 1497–1500, 1974.
 4. Arendshorst, W. J., and C. W. Gottschalk. Glomerular ultrafiltration dynamics: historical perspective. Am. J. Physiol. 248 (Renal Fluid Electrolyte Physiol. 17): F163–F174, 1985.
 5. Aukland, K., and A. H. Oien. Renal autoregulation: models combining tubuloglomerular feedback and myogenic response. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F768–F783, 1987.
 6. Baines, A. D., D. Basmadjian, and B. C. Wang. Computer simulation of flow‐dependent absorption in microperfused short Henle's loop of rats. Biophys. J. 27: 21–38, 1979.
 7. Bartoli, E., and L. E. Earley. Measurement of nephron filtration rate in the rat with and without occlusion of the proximal rubule. Kidney Int. 3: 372–380, 1973.
 8. Baylis, C., and R. C. Blantz. Tubuloglomerular feedback activity in virgin and 12‐day‐pregnant rats. Am. J. Physiol. 249 (Renal Fluid Electrolyte Physiol. 18): F169–F173, 1985.
 9. Bell, P. D. Cyclic AMP–calcium interaction in the transmission of tubuloglomerular feedback signals. Kidney Int. 28: 728–732, 1985.
 10. Bell, P. D. Tubuloglomerular feedback responses in the rat during calmodulin inhibition. Am. J. Physiol. 250 (Renal Fluid Electrolyte Physiol. 19): F715–F719, 1986.
 11. Bell, P. D., M. Franco, and L. G. Navar. Calcium as a mediator of tubuloglomerular feedback. Annu. Rev. Physiol. 49: 275–293, 1987.
 12. Bell, P. D., M. Franco‐Guevara, D. R. Abrahamson, J.‐Y. Lapointe, and J. Cardinal. Cellular mechanisms for tubuloglomerular feedback signaling. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg, Amsterdam: Elsevier, pp. 63–77.
 13. Bell, P. D., J.‐Y. Lapointe, and J. Cardinal. Direct measurement of basolateral potentials from cells of the macula densa. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F463–F468, 1989.
 14. Bell, P. D., C. McLean, and L. G. Navar. Dissociation of tubuloglomerular feedback responses from distal tubular chloride concentration in the rat. Am. J. Physiol. 240 (Renal Fluid Electrolyte Physiol. 9): F111–F119, 1981.
 15. Bell, P. D., and L. G. Navar. Relationship between tubuloglomerular feedback responses and perfusate hypotonicity. Kidney Int. 22: 234–239, 1982.
 16. Bell, P. D., and L. G. Navar. Cytoplasmic calcium in the mediation of macula densa tubuloglomerular feedback responses. Science 215: 670–673, 1982.
 17. Bell, P. D., L. G. Navar, D. W. Ploth, and C. B. McLean. Tubuloglomerular feedback responses during perfusion with nonelectrolyte solutions in the rat. Kidney Int. 18: 460–471, 1980.
 18. Bell, P. D., and M. Reddington. Intracellular calcium in the transmission of tubuloglomerular feedback signals. Am. J. Physiol. 245 (Renal Fluid Electrolyte Physiol. 14): F295–F302, 1983.
 19. Bell, P. D., M. Reddington, D. Ploth, and L. G. Navar. Tubuloglomerular feedback‐mediated decreases in glomerular pressure in Munich‐Wistar rats. Am. J. Physiol. 247 (Renal Fluid Electrolyte Physiol. 16): F877–F880, 1984.
 20. Bell, P. D., C. Thomas, R. H. Williams, and L. G. Navar. Filtration rate and stop‐flow pressure feedback responses to nephron perfusion in the dog. Am. J. Physiol. 234 (Renal Fluid Electrolyte Physiol. 3): F154–F165, 1978.
 21. Blaine, E. H., J. O. Davis, and R. T. Witty. Renin release after hemorrhage and after suprarenal aortic constriction in dogs without sodium delivery to the macula densa. Circ. Res. 27: 1081–1089, 1970.
 22. Blantz, R. C., and K. S. Konnen. Relation of distal tubular delivery and reabsorptive rate to nephron filtration. Am. J. Physiol. 233 (Renal Fluid Electrolyte Physiol. 2): F315–F324, 1977.
 23. Blantz, R. C., K. Konnen, and B. J. Tucker. Glomerular filtration response to elevated ureteral pressure in both the hydropenic and plasma expanded rat. Circ. Res. 37: 819–829, 1975.
 24. Blantz, R. C., and J. C. Pelayo. A functional role for the tubuloglomerular feedback mechanism. Kidney Int. 25: 739–746, 1984.
 25. Blantz, R. C., and O. W. Peterson. Effect of acute nephrectomy on tubuloglomerular feedback activity in the rat. Kidney Int. 35: 467, 1989.
 26. Blantz, R. C., O. W. Peterson, L. Gushwa, and B. J. Tucker. Effect of modest hyperglycemia upon tubuloglomerular feedback activity. Kidney Int. 22 (Suppl. 12): S206–S212, 1982.
 27. Blantz, R. C., B. J. Tucker, L. Gushwa, and O. W. Peterson. Mechanism of diuresis following acute modest hyperglycemia in the rat. Am. J. Physiol. 244 (Renal Fluid Electrolyte Physiol. 13): F185–F194, 1983.
 28. Boberg, U., B. Hahne, and A. E. G. Persson. Resetting of the tubuloglomerular feedback control (TGF) with intraarterial infusion of prostacyclin. Acta Physiol. Scand. 121: 65–72, 1984.
 29. Boberg, U., and A. E. G. Persson. Tubuloglomerular feedback during elevated renal venous pressure. Am. J. Physiol. 249 (Renal Fluid Electrolyte Physiol. 18): F524–F531, 1985.
 30. Boberg, U., and A. G. E. Persson. Increased tubuloglomerular feedback activity in Milan hypertensive rats. Am. J. Physiol. 250 (Renal Fluid Electrolyte Physiol. 19): F967–F974, 1986.
 31. Boberg, U., and F. S. Wright. Distal NaCl concentration as signal for the tubuloglomerular feedback mechanism. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 89–96.
 32. Boknam, L., E.‐C. Ericson, B. Aberg, and H. R. Ulfendahl. Flow resistance of the interlobular artery in the rat kidney. Acta Physiol. Scand. 111: 159–164, 1981.
 33. Bouby, N., M.‐M. Trinh‐Trang‐Tan, W. Kriz, and L. Bankir. Possible role of the thick ascending limb and of the urine concentrating mechanism in the protein‐induced increase in GFR and kidney mass. Kidney Int. 32 (Suppl. 22): S57–S61, 1987.
 34. Briggs, J. P. A simple steady‐state model for feedback control of glomerular filtration rate. Kidney Int. 22 (Suppl. 12): S143–S150, 1982.
 35. Briggs, J. P. Effect of loop of Henle flow rate on glomerular capillary pressure. Renal Physiol. 7: 311–320, 1984.
 36. Briggs, J. P., and J. Schnermann. The effect of metabolic inhibitors on feedback response of nephron filtration rate. Pflugers Arch. 389 (Suppl.): R40, 1981.
 37. Briggs, J. P., and J. Schnermann. Regulatory role of the tubuloglomerular feedback mechanism. In: Nephrology, edited by R. R. Robinson. New York: Springer‐Verlag, vol. 1, 1984, pp. 143–153.
 38. Briggs, J. P., and J. Schnermann. Macula densa control of renin secretion and glomerular vascular tone: evidence for common cellular mechanisms. Renal Physiol. 9: 193–203, 1986.
 39. Briggs, J. P., and J. Schnermann. The tubuloglomerular feedback mechanism: functional and biochemical aspects. Annu. Rev. Physiol. 49: 251–273, 1987.
 40. Briggs, J. P., J. Schnermann, and F. S. Wright. Failure of tubule fluid osmolarity to affect feedback regulation of glomerular filtration. Am. J. Physiol. 239 (Renal Fluid Electrolyte Physiol. 8): F427–F432, 1980.
 41. Briggs, J. P., G. Schubert, and J. Schnermann. Further evidence for an inverse relationship between macula densa NaCl concentration and filtration rate. Pflugers Arch. 392: 372–378, 1982.
 42. Briggs, J. P., G. Schubert, and J. Schnermann. Quantitative characterization of the tubuloglomerular feedback response: effect of growth. Am. J. Physiol. 247 (Renal Fluid Electrolyte Physiol. 16): F808–F815, 1984.
 43. Briggs, J. P., B. Steipe, G. Schubert, and J. Schnermann. Micropuncture studies of the renal effects of atrial natriuretic substance. Pflugers Arch. 395: 271–276, 1982.
 44. Briggs, J. P., and F. S. Wright. Feedback control of glomerular filtration rate: site of the effector mechanism. Am. J. Physiol. 236 (Renal Fluid Electrolyte Physiol. 5): F40–F47, 1979.
 45. Brunkhorst, R., K. Müller‐Ott, H.‐U. Gutsche, and W. Niedermayer. Effect of furosemide, bumetanide, and piretanide on the sensor of the tubuloglomerular feedback mechanism. Proc. Eur. Dial. Transplant. Assoc. 15: 613–616, 1978.
 46. Bührle, C., R. Nobiling, and R. Taugner. Intracellular recordings from renin‐positive cells of the afferent glomerular arteriole. Am. J. Physiol. 249 (Renal Fluid Electrolyte Physiol. 18): F272–F281, 1985.
 47. Bührle, C., L. Rosivall, and R. Taugner. Intrarenal generation of angiotensin II evaluated by an electrophysiological technique. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F635–F644, 1987.
 48. Bührle, C., H. Scholz, R. Nobiling, and R. Taugner. Junctional transmission in renin‐containing and smooth muscle cells of the afferent arteriole. Pflugers Arch. 406: 578–586, 1986.
 49. Burke, T. J., L. G. Navar, J. R. Clapp, and R. R. Robinson. Response of single nephron glomerular filtration rate to distal nephron microperfusion. Kidney Int. 6: 230–240, 1974.
 50. Casellas, D., and L. C. Moore. Autoregulation and tubuloglomerular feedback in juxtamedullary glomerular arterioles. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F660–F669, 1990.
 51. Casellas, D., P. Morsing, A. Stenberg, A. E. G. Persson. The juxtamedullary nephron preparation: a tool in tubuloglomerular feedback studies. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 189–199.
 52. Celio, M. R., and T. Inagami. Angiotensin II immunoreactivity coexists with renin in the juxtaglomerular granular cells of the kidney. Proc. Natl. Acad. Sci. USA 78: 3897–3900, 1981.
 53. Chou, C. L., and D. J. Marsh. Role of proximal convoluted tubule in pressure diuresis in the rat. Am. J. Physiol. 251 (Renal Fluid Electrolyte Physiol. 20): F283–F289, 1986.
 54. Coelho, J. B., K. C. H. Chien, and S. E. Bradley. Measurement of single nephron glomerular filtration rate without micropuncture. Am. J. Physiol. 223: 832–839, 1972.
 55. Cortney, M. A., W. Nagel, and K. Thurau. A micropuncture study of the relationship between flow rate through the loop of Henle and sodium concentration in the distal tubule. Pflugers Arch. 287: 286–295, 1966.
 56. al Canton, A., A. Corradi, R. Stanziale, G. Maruccio, and A. Migone. Effects of 24 hour unilateral ureteral obstruction on glomerular hemodynamics in rat kidney. Kidney Int. 15: 457–462, 1979.
 57. Dal Canton, A., R. Stanziale, A. Corradi, V. Andreucci, and A. Migone. Effects of acute ureteral obstruction on glomerular hemodynamics in rat kidney. Kidney Int. 12: 403–411, 1977.
 58. Daniels, F. H., and W. J. Arendshorst. Autoregulation of renal blood flow in the rat is mediated by two different mechanisms. FASEB J. 4: A1077, 1990.
 59. Daniels, F. H., and W. J. Arendshorst. Tubuloglomerular feedback kinetics in spontaneously hypertensive and Wistar‐Kyoto rats. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F529–F534, 1990.
 60. Daniels, F. H., W. J. Arendshorst, and R. G. Roberds. Tubuloglomerular feedback and autoregulation in sponta‐neously hypertensive rats. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F1479–F1489, 1990.
 61. Dantzler, W. H. Comparative aspects of renal function. In: The Kidney, Physiology and Pathophysiology, edited by D. W. Seldin and G. Giebisch. New York: Raven Press, vol. 1, 1985, pp. 333–364.
 62. Davis, J. M. Proximal tubular stop flow pressure: an index of glomerular capillary pressure? Pflugers Arch. 417: 264–268, 1990.
 63. Davis, J. M., D. A. Häberle, and T. Kawata. The control of glomerular filtration rate and renal blood flow in chronically volume expanded rats. J. Physiol. 402: 473–495, 1988.
 64. Davis, J. M., D. A. Häberle, T. Kawata, E. Schmitt, T. Takabatake, and S. Wohlfeil. Increased tubuloglomerular feedback mediated suppression of glomerular filtration during acute volume expansion in rats. J. Physiol. 395: 553–576, 1988.
 65. Davis, J. M., T. Kawata, and D. A. Häberle. The influence of renal autoregulation on TGF control of glomerular filtration rate. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 393–406.
 66. Davis, J. M., and J. Schnermann. The effect of antidiuretic hormone on the distribution of nephron filtration rates in rats with hereditary diabetes insipidus. Pflugers Arch. 330: 323–334, 1971.
 67. Davis, J. M., J. Schnermann, and M. Horster. Micropuncture method for the determination of nephron filtration rate. A recollection study. Pflugers Arch. 333: 271–280, 1972.
 68. Davis, J. M., T. Takabatake, T. Kawata, and D. A. Haeberle. Resetting of tubuloglomerular feedback in acute volume expansion in rats. Pflugers Arch. 411: 322–327, 1988.
 69. Davis, J. M., T. Takabatake, K. Thurau, and D. A. Haeberle. The effect of muzolimine on the tubuloglomerular feedback mechanism in the rat kidney. Z. Kardiol. 74 (Suppl. 2): 161–165, 1985.
 70. Deray, G., R. Sabra, W. A. Herzer, E. K. Jackson, and R. A. Branch. Interaction between angiotensin II and adenosine in mediating the vasoconstrictor response to intrarenal hypertonic saline infusions in the dog. J. Pharmacol. Exp. Ther. 252: 631–635, 1990.
 71. Dev, B., C. Drescher, and J. Schnermann. Resetting of tubuloglomerular feedback sensitivity by dietary salt intake. Pflugers Arch. 346: 263–277, 1974.
 72. Dilley, J. R., and W. J. Arendshorst. Enhanced tubuloglomerular feedback activity in rats developing spontaneous hypertension. Am. J. Physiol. 247 (Renal Fluid Electrolyte Physiol. 16): F672–F679, 1984.
 73. Dilley, J. R., C. T. Stier, and W. J. Arendshorst. Abnormalities in glomerular function in rats developing spontaneous hypertension. Am. J. Physiol. 246 (Renal Fluid Electrolyte Physiol. 15): F12–F20, 1984.
 74. DuBose, T. D., D. W. Seldin, and J. P. Kokko. Segmental chloride reabsorption in the rat nephron as a function of load. Am. J. Physiol. 234 (Renal Fluid Electrolyte Physiol. 3): F97–F105, 1978.
 75. Edwards, R. M. Segmental effects of norepinephrine and angiotensin II on isolated renal microvessels. Am. J. Physiol. 244 (Renal Fluid Electrolyte Physiol. 13): F526–F534, 1983.
 76. Ericson, A.‐C., M. Sjoequist, and H. R. Ulfendahl. Heterogeneity in regulation of glomerular function. Acta Physiol. Scand. 114: 203–209, 1982.
 77. Folkow, B. Physiological aspects of primary hypertension. Physiol. Rev. 62: 347–504, 1982.
 78. Franco, M., P. D. Bell, and L. G. Navar. Evaluation of prostaglandins as mediators of tubuloglomerular feedback. Am. J. Physiol. 254 (Renal Fluid Electrolyte Physiol. 23): F642–F649, 1988.
 79. Franco, M., P. D. Bell, and L. G. Navar. Effect of adenosine A1 analogue on tubuloglomerular feedback mechanism. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F231–F236, 1989.
 80. Gabbai, F. B., L. C. Gushwa, O. W. Peterson, C. B. Wilson, and R. C. Blantz. Analysis of renal function in the two‐kidney Goldblatt model. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F131–F137, 1987.
 81. Galla, J. H., D. N. Bonduris, P. W. Sanders, and R. G. Luke. Volume‐independent reductions in glomerular filtration rate in acute chloride‐depletion alkalosis in the rat. Evidence for mediation by tubuloglomerular feedback. J. Clin. Invest. 74: 2002–2008, 1984.
 82. Gerber, J. G., R. A. Branch, A. S. Nies, J. W. Hollifield, and J. F. Gerkens. Influence of hypertonic saline on canine renal blood flow and renin release. Am. J. Physiol. 237 (Renal Fluid Electrolyte Physiol. 6): F441–F446, 1979.
 83. Gerkens, J. F., and R. A. Branch. The influence of sodium status and furosemide on canine acute amphotericin B nephrotoxicity. J. Pharmacol. Exp. Ther. 214: 306–311, 1980.
 84. Gerkens, J. F., H. T. Heidemann, E. K. Jackson, and R. A. Branch. Aminophylline inhibits renal vasoconstriction produced by intrarenal hypertonic saline. J. Pharmacol. Exp. Ther. 225: 611–615, 1983.
 85. Gertz, K. H., J. A. Mangos, G. Braun, and H. D. Pagel. Pressure in the glomerular capillaries of the rat kidney and its relation to arterial blood pressure. Pflugers Arch. 288: 369–374, 1966.
 86. Gillies, A., and T. Morgan. Renin content of individual juxtaglomerular apparatuses and the effect of diet, changes in nephron flow rate and in vitro acidification. Pflugers Arch. 375: 105–110, 1978.
 87. Gillies, A., and T. Morgan. Modification of renin content in individual juxtaglomerular apparatus. In: Proceedings of the 7th Int. Congr. Nephrol., Montreal, F‐11 Abstract, 1978.
 88. Gillies, A., and T. Morgan. Activity of renin in the juxtaglomerular apparatus. Kidney Int. 22 (Suppl. 12): S67–S72, 1982.
 89. Golgi, C. Annotazioni intorno all'istologia dei reni dell'uomo e di altri mammiferi e sull'istogenesi dei canalicoli oriniferi. Atti della Reale Accademia dei Lincei 5: 334–342, 1889.
 90. Gonzalez, E., M. Salomonsson, C. Müller‐Suur, and A. E. G. Persson. Measurements of macula densa cell volume changes in isolated and perfused rabbit cortical thick ascending limb. I. Isosmotic and anisosmotic cell volume changes. Acta Physiol. Scand. 133: 149–157, 1988.
 91. Gonzalez, E., M. Salomonsson, C. Müller‐Suur, and A. E. G. Persson. Measurements of macula densa cell volume changes in isolated and perfused rabbit cortical thick ascending limb. II. Apical and basolateral cell osmotic water permeabilities. Acta Physiol. Scand. 133: 159–166, 1988.
 92. Goormaghtigh, N. Les segments neuro‐myo‐artériels juxtaglomerulaires du rein. Arch. Biol. 43: 575–591, 1932.
 93. Goormaghtigh, N. L'appareil neuro‐myo‐artériel juxtaglomerulaire du rein; ses réactions en pathologie et ses rapports avec le tube urinifére. C. R. Soc. Biol. 124: 293–296, 1937.
 94. Greger, R. Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol. Rev. 65: 760–797, 1985.
 95. Gutsche, H.‐U., R. Müller‐Suur, U. Hegel, and K. Hierholzer. Electrical conductivity of tubular fluid of the rat nephron. Micropuncture study of the diluting segment in situ. Pflugers Arch. 383: 113–122, 1980.
 96. Gutsche, H.‐U., R. Müller‐Suur, K. F. Samwer, G. Beer, and K. Hierholzer. Tubuloglomerular feedback control in kidneys of adrenalectomized rats. Pflugers Arch. 386: 11–20, 1980.
 97. Guyton, A. C. Theory for autoregulation of glomerular filtration rate and blood flow in each nephron by the juxtaglomerular apparatus. Physiologist 6: 194, 1963.
 98. Guyton, A. C., J. B. Langston, and L. G. Navar. Theory for renal autoregulation by feedback of the juxtaglomerular apparatus. Circ. Res. [Suppl. I], 14s, 15: 1187–1196, 1964.
 99. Häberle, D. Influence of glomerular filtration rate on the rate of p‐aminohippurate secretion by the rat kidney: micropuncture and clearance studies. Kidney Int. 7: 385–396, 1975.
 100. Häberle, D. A. Hemodynamic interactions between intrinsic blood flow control mechanisms in the rat kidney. Renal Physiol. Biochem. 11: 289–315, 1988.
 101. Häberle, D., and J. M. Davis. Interrelationship between proximal tubular hydrodynamics and tubuloglomerular feedback in the rat kidney. Kidney Int. 22 (Suppl. 12): S193–S197, 1982.
 102. Häberle, D. A., and J. M. Davis. Chronic salt loading. Effects on plasma volume and regulation of filtration rate in Wistar rats. Klin. Wochenschr. 60: 1245–1248, 1982.
 103. Häberle, D., and J. M. Davis. Resetting of tubuloglomerular feedback: evidence for a humoral factor in tubular fluid. Am. J. Physiol. 246 (Renal Fluid Electrolyte Physiol. 15): F495–F500, 1984.
 104. Häberle, D. A., and J. M. Davis. Tubuloglomerular feedback mechanisms: interrelationships between tubular flow and glomerular filtration rate. In: Advances in Renal Physiology, edited by C. J. Lote. London: Croome, Helm Ltd, 1986, pp. 114–137.
 105. Häberle, D. A., J. M. Davis, T. Kawata, H. Dahlheim, and E. Schmitt. The effect of acute adrenalectomy on the resetting of tubuloglomerular feedback and renal renin release in chronic volume expansion. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 177–188.
 106. Häberle, D. A., T. Kawata, and J. M. Davis. The site of action of nitrendipine in the rat kidney. J. Cardiovasc. Pharmacol. 9 (Suppl. 1): S17–S23, 1987.
 107. Häberle, D. A., T. Kawata, and J. M. Davis. Interference by the tubuloglomerular feedback mechanism with the action of diuretics. In: Diuretics II. Chemistry, Pharmacology and Clinical Applications, edited by J. B. Puschett and A. Greenberg. New York: Elsevier, 1987, pp. 150–158.
 108. Häberle, D. A., B. Königbauer, J. M. Davis, T. Kawata, C. Mast, C. Metz, and H. Dahlheim. Autoregulation of the glomerular filtration rate and the single glomerular filtration rate despite inhibition of tubuloglomerular feedback in rats chronically volume‐expanded by deoxycorticosterone acetate. Pflugers Arch. 416: 548–553, 1990.
 109. Häberle, D., T. T. Shiigai, G. Maier, H. Schiffl, and J. M. Davis. Dependency of proximal fluid transport on the load of glomerular filtrate. Kidney Int. 20: 18–28, 1981.
 110. Hahne, B., and A. E. G. Persson. Prevention of interstitial pressure change at unilateral nephrectomy by prostaglandin synthesis inhibition. Kidney Int. 25: 42–46, 1984.
 111. Hahne, B., G. Selen, and A. E. G. Persson. Indomethacin inhibits renal functional adaptation to nephron loss. Renal Physiol. 7: 13–21, 1984.
 112. Harsing, L., S. Fonyodi, M. Kabat, and G. Koever. Effect of phlorizin and of mercurial diuretics on renal haemodynamics. Acta Physiol. Acad. Sci. Hung. 12: 363–371, 1957.
 113. Hermansson, K., K. Källskog, and M. Wolgast. Effect of renal nerve stimulation on the activity of the tubuloglomerular feedback mechanism. Acta Physiol. Scand. 120: 381–386, 1984.
 114. Heyeraas Tonder, K. J., and K. Aukland. Interlobular arterial pressure in the rat kidney. Renal Physiol. 2: 214–221, 1979/80.
 115. Hierholzer, K., R. Müller‐Suur, H.‐U. Gutsche, M. Butz, and I. Lichtenstein. Filtration in surface glomeruli as regulated by flow through the loop of Henle. Pflugers Arch. 352: 315–337, 1974.
 116. Holstein‐Rathlou, N.‐H. Synchronization of proximal intratubular pressure oscillations: evidence for interaction between nephrons. Pflugers Arch. 408: 438–443, 1987.
 117. Holstein‐Rathlou, N.‐H., and P. P. Leyssac. TGF‐mediated oscillations in the proximal intratubular pressure: differences between spontaneously hypertensive rats and Wistar‐Kyoto rats. Acta Physiol. Scand. 126: 333–339, 1986.
 118. Holstein‐Rathlou, N.‐H., and P. P. Leyssac. Oscillations in the proximal intratubular pressure: a mathematical model. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F560–F572, 1987.
 119. Holstein‐Rathlou, N.‐H., and D. J. Marsh. Oscillations of tubular pressure, flow and distal chloride concentration. Am. J. Physiol. 256 (Renal Fluid Electrolyte Physiol. 25): F1007–F1014, 1989.
 120. Holstein‐Rathlou, N.‐H., and D. J. Marsh. A dynamic model of the tubuloglomerular feedback mechanism. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F1448–F1459, 1990.
 121. Holstein‐Rathlou, N.‐H., A. J. Wagner, and D. J. Marsh. Response of renal blood flow to periodic forcing of arterial pressure. FASEB J. 4: A1077, 1990.
 122. Holz, F. G., and M. Steinhausen. Renovascular effects of adenosine receptor agonists. Renal Physiol. 10: 272–282, 1987.
 123. Huang, C. L., and M. G. Cogan. Atrial natriuretic factor inhibits maximal tubuloglomerular feedback response. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F825–F828, 1987.
 124. Huang, C. L., J. Lewicki, L. K. Johnson, and M. G. Cogan. Renal mechanism of action of rat atrial natriuretic factor. J. Clin. Invest. 75: 769–773, 1985.
 125. Huang, W.‐C., P. D. Bell, D. Harvey, K. D. Mitchell, and L. G. Navar. Angiotensin influences on tubuloglomerular feedback mechanism in hypertensive rats. Kidney Int. 34: 631–637, 1988.
 126. Ichikawa, I. Evidence for altered glomerular hemodynamics during acute nephron obstruction. Am. J. Physiol. 242 (Renal Fluid Electrolyte Physiol. 11): F580–F585, 1982.
 127. Ichikawa, I. Direct analysis of the effector mechanism of the tubuloglomerular feedback system. Am. J. Physiol. 243 (Renal Fluid Electrolyte Physiol. 12): F447–F455, 1982.
 128. Jamison, R. L. Micropuncture study of superficial and juxtamedullary nephrons in the rat. Am. J. Physiol. 218: 46–55, 1970.
 129. Jensen, P. K., K. S. Kristensen, R. Rasch, and A. E. G. Persson. Decreased sensitivity of the tubuloglomerular feedback mechanism in experimental diabetic rats. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 333–338.
 130. Kaissling, B., and W. Kriz. Variability of intercellular spaces between macula densa cells: a transmission electron microscopic study in rabbits and rats. Kidney Int. 22 (Suppl. 12): S9–S17, 1982.
 131. Källskog, Ö., and D. J. Marsh. TGF‐initiated vascular interactions between adjacent nephrons in the rat kidney. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F60–F64, 1990.
 132. Kashgarian, M., D. Biemesderfer, M. Caplan, and B. Forbush. Monoclonal antibodies to Na‐K‐ATPase: immunocytochemical localization along nephron segments. Kidney Int. 28: 899–913, 1985.
 133. Kaskel, F. J., P. Devarajan, L. A. Arbeit, J. S. Partin, and L. C. Moore. Cyclosporine nephrotoxicity: sodium excretion, autoregulation, and angiotensin II. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F733–F742, 1987.
 134. Kaskel, F. J., P. Devarajan, A. Birzgalis, and L. C. Moore. Inhibition of myogenic autoregulation in cyclosporine nephrotoxicity in the rat. Renal Physiol. Biochem. 12: 250–259, 1989.
 135. Kaufman, J. S., R. J. Hamburger, and W. Flamenbaum. Tubuloglomerular feedback: effect of dietary NaCl intake. Am. J. Physiol. 231: 1744–1749, 1976.
 136. Kaufman, J. S., R. J. Hamburger, and W. Flamenbaum. Tubuloglomerular feedback response after hypotensive hemorrhage. Renal Physiol. 5: 173–181, 1982.
 137. Kinne, R., B. Koenig, J. Hannafin, E. Kinne‐Saffran, D. M. Scott, and K. Zierold. The use of membrane vesicles to study the NaCl/KCl cotransporter involved in active chloride transport. Pflugers Arch. 405 (Suppl. 1): S101–S105, 1985.
 138. Kirk, K. L., P. D. Bell, D. Barfuss, and M. Ribadeneira. Direct visualization of the isolated and perfused macula densa. Am. J. Physiol. 248 (Renal Fluid Electrolyte Physiol. 17): F890–F894, 1985.
 139. Knox, F. G., C. Ott, J.‐L. Cuche, J. Gasser, and J. Haas. Autoregulation of single nephron filtration rate in the presence and the absence of flow to the macula densa. Circ. Res. 34: 836–842, 1974.
 140. Kremer, S. G., W. B. Breuer, and K. L. Skorecki. Vasoconstrictor hormones depolarize renal glomerular mesangial cells by activating Cl channels. J. Cell. Physiol. 138: 97–105, 1989.
 141. Kurtz, A. Cellular control of renin secretion. Rev. Physiol. Biochem. Pharmacol. 113: 1–40, 1989.
 142. Kurtz, A., and R. Penner. Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells. Proc. Natl. Acad. Sci. USA 86: 3423–3427, 1989.
 143. Landwehr, D. M., J. Schnermann, R. M. Klose, and G. Giebisch. The effect of acute reduction in glomerular filtration rate on renal tubular sodium and water reabsorption. Am. J. Physiol. 215: 687–695, 1968.
 144. Lapointe, J.‐Y., P. D. Bell, and J. Cardinal. Direct evidence for apical Na+ :2Cl−:K+ cotransport in macula densa cells. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F1466–F1469, 1990.
 145. Leyssac, P. P. Further studies on oscillating tubulo‐glomerular feedback responses in the rat kidney. Acta Physiol. Scand. 126: 271–277, 1986.
 146. Leyssac, P. P. Changes in single nephron renin release are mediated by tubular fluid flow rate. Kidney Int. 30: 332–339, 1986.
 147. Leyssac, P. P., and L. Baumbach. An oscillating intratubular pressure response to alterations in Henle loop flow in the rat kidney. Acta Physiol. Scand. 117: 415–419, 1983.
 148. Leyssac, P. P., and N.‐H. Holstein‐Rathlou. Effects of various transport inhibitors on oscillating TGF pressure responses in the rat. Pflugers Arch. 407: 285–291, 1986.
 149. Leyssac, P. P., P. K. Jensen, and N.‐H. Holstein‐Rathlou. A study of proximal tubular compliances in normotensive and spontaneously hypertensive rats, and the effect of anesthesia on the compliance. Acta Physiol. Scand. 126: 341–348, 1986.
 150. Lorenz, J. N., H. Weihprecht, J. Schnermann, O. Skøtt, and J. P. Briggs. Characterization of the macula densa stimulus for renin secretion. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F186–F193, 1990.
 151. Maddox, D. A., J. L. Troy, and B. M. Brenner. Autoregulation of filtration rate in the absence of macula densaglomerulus feedback. Am. J. Physiol. 227: 123–131, 1974.
 152. Mason, J., H.‐U. Gutsche, L. Moore, and R. Mueller‐Suur. The early phase of experimental acute renal failure. IV. The diluting ability of the short loops of Henle. Pflugers Arch. 379: 11–18, 1979.
 153. Mason, J., H. Kain, T. Shiigai, and J. Welsch. The early phase of experimental acute renal failure. V. The influence of suppressing the renin‐angiotensin system. Pflugers Arch. 380: 233–243, 1979.
 154. Mason, J., H. Kain, J. Welsch, and J. Schnermann. The early phase of experimental acute renal failure. VI. The influence of furosemide. Pflugers Arch. 392: 125–133, 1981.
 155. Mason, J., T. Takabatake, C. Olbricht, and K. Thurau. The early phase of experimental acute renal failure. III. Tubuloglomerular feedback. Pflugers Arch. 373: 69–76, 1978.
 156. Mitchell, K. D., and L. G. Navar. Enhanced tubuloglomerular feedback during peritubular perfusions of angiotensins I and II. Am. J. Physiol. 255 (Renal Fluid Electrolyte Physiol. 24): F383–F390, 1988.
 157. Mitchell, K. D., and L. G. Navar. Tubuloglomerular feedback responses during peritubular infusions of calcium channel blockers. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F537–F544, 1990.
 158. Moore, L. C. Tubuloglomerular feedback in hamster superficial and juxtamedullary nephrons. Federation Proc. 41: A5763, 1982.
 159. Moore, L. C. Tubuloglomerular feedback and SNGFR autoregulation in the rat. Am. J. Physiol. 247 (Renal Fluid Electrolyte Physiol. 16): F267–F276, 1984.
 160. Moore, L. C., and D. Casellas. Tubuloglomerular feedback dependence of autoregulation in rat juxtamedullary afferent arterioles. Kidney Int. 37: 1402–1408, 1990.
 161. Moore, L. C., and J. Mason. Perturbation analysis of tubuloglomerular feedback in hydropenic and hemorrhaged rats. Am. J. Physiol. 245 (Renal Fluid Electrolyte Physiol. 14): F554–F563, 1983.
 162. Moore, L. C., and J. Mason. Tubuloglomerular feedback control: effect of extracellular volume. Am. J. Physiol. 250 (Renal Fluid Electrolyte Physiol. 19): F1024–F1032, 1986.
 163. Moore, L. C., and A. Rich. Mathematical model of ascending myogenic responses to tubuloglomerular feedback induced changes in afferent vascular resistance. Kidney Int. 33: 412, 1988.
 164. Moore, L. C., J. Schnermann, and S. Yarimizu. Feedback mediation of SNGFR autoregulation in hydropenic and DOCA‐and salt‐loaded rats. Am. J. Physiol. 237 (Renal Fluid Electrolyte Physiol. 6): F63–F74, 1979.
 165. Moore, L. C., S. Yarimizu, G. Schubert, P. C. Weber, and J. Schnermann. Dynamics of tubuloglomerular feedback adaptation to acute and chronic changes in body fluid volume. Pflugers Arch. 387: 39–45, 1980.
 166. Morgan, T., and R. W. Berliner. A study by continuous microperfusion of water and electrolyte movements in the loop of Henle and distal tubule of the rat. Nephron 6: 388–405, 1969.
 167. Morsing, P., and A. E. G. Persson. Pelvic pressure and tubuloglomerular feedback in hydronephrosis. Renal Physiol. Biochem. 13: 181–189, 1990.
 168. Morsing, P., A. Stenberg, C. Müller‐Suur, and A. E. G. Persson. Tubuloglomerular feedback in animals with unilateral, partial ureteral occlusion. Kidney Int. 32: 212–218, 1987.
 169. Morsing, P., A. Stenberg, C. Müller‐Suur, and A. E. G. Persson. Tubuloglomerular feedback in animals with partial ureteral occlusion. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 339–349.
 170. Morsing, P., A. Stenberg, and A. E. G. Persson. Effect of thromboxane inhibition on tubuloglomerular feedback in hydronephrotic kidneys. Kidney Int. 36: 447–452, 1989.
 171. Müller‐Suur, R., and H.‐U. Gutsche. Effect of intratubular substitution of Na and Cl− ions on operation of tubuloglomerular feedback. Acta Physiol. Scand. 103: 353–362, 1978.
 172. Müller‐Suur, R., H.‐U. Gutsche, K. F. Samwer, W. Oelkers, and K. Hierholzer. Tubuloglomerular feedback in rat kidneys of different renin content. Pflugers Arch. 359: 33–56, 1975.
 173. Müller‐Suur, R., H.‐U. Gutsche, and H. J. Schurek. Acute and reversible inhibition of tubuloglomerular feedback mediated afferent vasoconstriction by calcium‐antagonist verapamil. In: Current Problems in Clinical Biochemistry, Renal Metabolism in Relation to Renal Function, edited by U. Schmidt and U. Dubach. Bern: H. Huber, 1977, pp. 291–298.
 174. Müller‐Suur, R., B. J. Norlén, and A. E. G. Persson. Resetting of tubuloglomerular feedback in rat kidneys after unilateral nephrectomy. Kidney Int. 18: 48–57, 1980.
 175. Müller‐Suur, R., and A. E. G. Persson. Influence of water‐diuresis or saline volume expansion on deep nephron tubuloglomerular feedback. Acta Physiol. Scand. 126: 139–146, 1986.
 176. Müller‐Suur, R., H. R. Ulfendahl, and A. E. G. Persson. Evidence for tubuloglomerular feedback in juxtamedullary nephrons of young rats. Am. J. Physiol. 244 (Renal Fluid Electrolyte Physiol. 13): F425–F431, 1983.
 177. Naruse, K., T. Inagami, M. R. Celio, R. J. Workman, and Y. Takii. Immunohistochemical evidence that angiotensin I and II are formed by intracellular mechanisms in juxtaglomerular cells. Hypertension 4 (Suppl. II): 70–74, 1982.
 178. Nashat, F. S., J. W. Tappin, and C. S. Wilcox. The renal blood flow and the glomerular filtration rate of anaesthetized dogs during acute changes in plasma sodium concentration. J. Physiol. 256: 731–745, 1976.
 179. Navar, L. G. The regulation of glomerular filtration rate in mammalian kidneys. In: Physiology of Membrane Disorders, edited by T. E. Andreoli, J. F. Hoffman, and D. D. Fanestil. New York: Plenum, 1978, pp. 593–627.
 180. Navar, L. G., P. D. Bell, C. E. Thomas, and D. W. Ploth. Influence of perfusate osmolality on stop‐flow pressure feedback responses in the dog. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F352–F358, 1978.
 181. Navar, L. G., T. J. Burke, R. R. Robinson, and J. R. Clapp. Distal tubular feedback in the autoregulation of single nephron glomerular filtration rate. J. Clin. Invest. 53: 516–525, 1974.
 182. Navar, L. G., B. Chomdej, and P. D. Bell. Absence of estimated glomerular capillary pressure autoregulation during interrupted distal delivery. Am. J. Physiol. 229: 1596–1603, 1975.
 183. Navar, L. G., D. W. Ploth, and P. D. Bell. Distal tubular feedback control of renal hemodynamics and autoregulation. Annu. Rev. Physiol. 42: 557–571, 1980.
 184. Norlén, B. J., R. Müller‐Suur, and A. E. G. Persson. Tubuloglomerular feedback response and excretory characteristics of the transplanted rat kidney. Scand. J. Urol. Nephrol. 12: 27–33, 1978.
 185. Odlind, B., B. Beermann, G. Selén, and A. E. G. Persson. Renal tubular secretion of piretanide and its effect on electrolyte reabsorption and tubuloglomerular feedback mechanism. J. Pharmacol. Exp. Ther. 225: 742–746, 1983.
 186. Okuda, T., N. Yamashita, and K. Kurokawa. Angiotensin II and vasopressin stimulate calcium‐activated chloride conductance in rat mesangial cells. J. Clin. Invest. 78: 1443–1448, 1986.
 187. Okuda, T., I. Kojima, E. Ogata, and K. Kurokawa. Ambient Cl− ions modify rat mesangial cell contraction by modulating cell inositol trisphosphate and Ca2+ via enhanced prostaglandin E2. J. Clin. Invest. 84: 1866–1872, 1989.
 188. Okusa, M. D., A. E. G. Persson, and F. S. Wright. Chlorothiazide effect on feedback‐mediated control of glomerular filtration rate. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F137–F144, 1989.
 189. Osswald, H., and H. Hermes. Stereospecific inhibition of the tubuloglomerular feedback and chloride transport in the loop of Henle by the new diuretic ozolinone. Kidney Int. 19: 251, 1981.
 190. Osswald, H., H. H. Hermes, and G. Nabakowski. Role of adenosine in signal transmission of tubuloglomerular feedback. Kidney Int. 22 (Suppl. 12): S136–S142, 1982.
 191. Osswald, H., G. Nabakowski, and H. Hermes. Adenosine as a possible mediator of metabolic control of glomerular filtration rate. Int. J. Biochem. 12: 263–267, 1980.
 192. Osswald, H., H.‐J. Schmitz, and O. Heidenreich. Adenosine response of the rat kidney after saline loading, sodium restriction and hemorrhagia. Pflugers Arch. 357: 323–333, 1975.
 193. Persson, A. E. G., G. Bianchi, and U. Boberg. Tubuloglomerular feedback in hypertensive rats of the Milan strain. Acta Physiol. Scand. 123: 139–146, 1985.
 194. Persson, A. E. G., L. G. Güshwa, and R. C. Blantz. Feedback pressure‐flow responses in normal and angiotensin‐prostaglandin‐blocked rats. Am. J. Physiol. 247 (Renal Fluid Electrolyte Physiol. 16): F925–F931, 1984.
 195. Persson, A. E. G., B. Hahne, and G. Selén. The effect of tubular perfusion with PGE2, PGF2, and PGI2 on the tubuloglomerular feedback control in the rat. Can. J. Physiol. Pharmacol. 61: 1317–1323, 1982.
 196. Persson, A. E. G., R. Müller‐Suur, and G. Selén. Capillary oncotic pressure as a modifier for tubuloglomerular feedback. Am. J. Physiol. 236 (Renal Fluid Electrolyte Physiol. 5): F97–F102, 1979.
 197. Persson, A. E. G., J. Schnermann, and F. S. Wright. Modification of feedback influence on glomerular filtration rate by acute isotonic extracellular volume expansion. Pflugers Arch. 381: 99–106, 1979.
 198. Persson, A. E. G., J. Wahlberg, R. Safirstein, and F. S. Wright. The effect of 2 hours of complete unilateral obstruction on tubuloglomerular feedback control. Acta Physiol. Scand. 122: 35–43, 1984.
 199. Persson, A. E. G., and F. S. Wright. Evidence for feedback mediated reduction of glomerular filtration rate during infusion of acetazolamide. Acta Physiol. Scand. 114: 1–7, 1982.
 200. Persson, B.‐E., and D. J. Marsh. GFR regulation and flow‐dependent electrophysiology of early distal tubule in Amphiuma. Am. J. Physiol. 253 (Renal Fluid Electrolyte Physiol. 22): F263–F268, 1987.
 201. Persson, B.‐E., and D. J. Marsh. The flow sensor of tubuloglomerular feedback in the early distal tubule of Amphiuma. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988. pp. 121–128.
 202. Persson, B.‐E., T. Sakai, M. Ekblom, and D. J. Marsh. Effect of bumetanide on tubuloglomerular feedback in Necturus maculosus. Acta Physiol. Scand. 137: 93–99, 1989.
 203. Persson, B.‐E., T. Sakai, and D. J. Marsh. Juxtaglomerular interstitial hypertonicity in Amphiuma: tubular origin‐TGF signal. Am. J. Physiol. 254 (Renal Fluid Electrolyte Physiol. 23): F445–F449, 1988.
 204. Persson, B.‐E., and A. E. G. Persson. The existence of a tubulo‐glomerular feedback mechanism in the Amphiuma nephron. Pflugers Arch. 391: 129–134, 1981.
 205. Peter, K. Ueber die Nierenkanaelchen des Menschen und einiger Saeugetiere. Anat. Amz. 30 (Suppl.): 114–127, 1907.
 206. Peterson, O. W., F. B. Gabbai, R. R. Myers, A. P. Mizisin, and R. C. Blantz. A single nephron model of acute tubular injury: role of tubuloglomerular feedback. Kidney Int. 36: 1037–1044, 1989.
 207. Peterson, O. W., L. C. Gushwa, C. B. Wilson, and R. C. Blantz. Tubuloglomerular feedback activity after glomerular immune injury. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F67–F71, 1989.
 208. Peterson, O. W., R. Rasch, B. J. Tucker, and R. C. Blantz. An examination of tubuloglomerular feedback activity in diabetic rats. Kidney Int. 37: 555, 1990.
 209. Pitman, E. B., and H. E. Layton. Tubuloglomerular feedback in a dynamic nephron. Commun. Pure Appl. Math. 42: 759–787, 1989.
 210. Ploth, D. W., H. Dahlheim, E. Schmidmeier, M. Hermle, and J. Schnermann. Tubuloglomerular feedback and autoregulation of glomerular filtration rate in Wistar‐Kyoto spontaneously hypertensive rats. Pflugers Arch. 375: 261–267, 1978.
 211. Ploth, D. W., and R. N. Roy. Renal and tubuloglomerular feedback effects of (Sar1,Ala8) angiotensin II in the rat. Am. J. Physiol. 242 (Renal Fluid Electrolyte Physiol. 11): F149–F157, 1982.
 212. Ploth, D. W., and R. N. Roy. Renin‐angiotensin influences on tubuloglomerular feedback activity in the rat. Kidney Int. 22 (Suppl. 12): S114–S121, 1982.
 213. Ploth, D. W., J. Rudulph, R. Lagrange, and L. G. Navar. Tubuloglomerular feedback and single nephron function after converting enzyme inhibition in the rat. J. Clin. Invest. 64: 1325–1335, 1979.
 214. Ploth, D. W., J. Rudulph, C. Thomas, and L. G. Navar. Renal and tubuloglomerular feedback response to plasma expansion in the rat. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F156–F162, 1978.
 215. Ploth, D. W., J. Schnermann, H. Dahlheim, M. Hermle, and F. Schmidmeier. Autoregulation and tubuloglomerular feedback in normotensive and hypertensive rats. Kidney Int. 12: 253–267, 1977.
 216. Pollock, D. M., and W. J. Arendshorst. Native tubular fluid attenuates ANF‐induced inhibition of tubuloglomerular feedback. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F189–F198, 1990.
 217. Pollock, D. M., and W. J. Arendshorst. Tubuloglomerular feedback and blood flow autoregulation during DA1‐induced renal vasodilation. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F627–F635, 1990.
 218. Rich, A., and L. C. Moore. Transport‐coupling hypothesis of tubuloglomerular feedback signal transmission. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F882–F892, 1989.
 219. Rosivall, L., and R. Taugner. Fluid balance in the interstitium of the Goormaghtigh cell field. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 39–49.
 220. Ruyter, J. C. Ueber einen merkwuerdigen Abschnitt der vasa afferentia in der Maeuseniere. Z. Zellforsch. Mikrosk. Anat. 2: 242–248, 1925.
 221. Safirstein, R., P. Miller, S. Dikman, N. Lyman, and C. Shapiro. Cisplatin nephrotoxicity in rats: defect in papillary hypertonicity. Am. J. Physiol. 241 (Renal Fluid Electrolyte Physiol. 10): F175–F185, 1981.
 222. Sakai, T., E. Hallman, and D. J. Marsh. Frequency domain analysis of renal autoregulation in the rat. Am. J. Physiol. 250 (Renal Fluid Electrolyte Physiol. 19): F364–F373, 1986.
 223. Sakai, T., F. H. Harris, D. J. Marsh, C. M. Bennett, and R. J. Glassock. Extracellular fluid expansion and autoregulation in nephrotoxic serum nephritis in rats. Kidney Int. 25: 619–628, 1984.
 224. Salomonsson, M., E. Gonzalez, L. Sjölin, and A. E. G. Persson. Simultaneous measurement of cytosolic free Ca2+ in macula densa cells and in cortical thick ascending limb cells using fluorescence digital imaging microscopy. Acta Physiol. Scand. 138: 425–426, 1990.
 225. Sanchez‐Ferrer, C. F., R. J. Roman, and D. R. Harder. Pressure‐dependent contraction of rat juxtamedullary afferent arterioles. Circ. Res. 64: 790–798, 1989.
 226. Savin, V. J. In vitro effects of angiotensin II on glomerular function. Am. J. Physiol. 251 (Renal Fluid Electrolyte Physiol. 20): F627–F634, 1986.
 227. Sawaya, B. P., J. N. Lorenz, J. A. Davis, J. P. Briggs, and J. Schnermann. The role of tubuloglomerular feedback activation in amphotericin‐B nephrotoxicity: a micropuncture study. Kidney Int. 37: 494, 1990.
 228. Schlatter, E., M. Salomonsson, A. E. G. Persson, and R. Greger. Macula densa cells sense luminal NaCl concentration via furosemide sensitive Na+2Cl−K+ cotransport. Pflugers Arch. 414: 286–290, 1989.
 229. Schlöndorff, D., and R. Ardaillou. Prostaglandins and other arachidonic acid metabolites in the kidney. Kidney Int. 29: 108–119, 1986.
 230. Schnabel, E., and W. Kriz. Morphometric studies of the extraglomerular mesangial cell field in volume expanded and volume depleted rats. Anat. Embryol. 170: 217–222, 1984.
 231. Schnermann, J. Regulation of single nephron filtration rate by feedback—facts and theories. Clin. Nephrol. 3: 75–81, 1975.
 232. Schnermann, J. Vascular tone as a determinant of tubuloglomerular feedback responsiveness. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988. pp. 167–176.
 233. Schnermann, J. Effect of adenosine analogues on tubuloglomerular feedback responses. Am. J. Physiol. 255 (Renal Fluid Electrolyte Physiol. 24): F33–F42, 1988.
 234. Schnermann, J., and J. P. Briggs. Concentration‐dependent sodium chloride transport as the signal in feedback control of glomerular filtration rate. Kidney Int. 22 (Suppl. 12): S82–S89, 1982.
 235. Schnermann, J., and J. P. Briggs. The effect of variations in protein intake on tubuloglomerular feedback and single nephron filtration rate in rats with normal and elevated blood pressures. Renal Physiol. 7: 258–259, 1984.
 236. Schnermann, J., and J. P. Briggs. Function of the juxtaglomerular apparatus: local control of glomerular hemodynamics. In: The Kidney: Physiology and Pathophysiology, edited by D. W. Seldin and G. Giebisch. New York: Raven, 1985. pp. 669–697.
 237. Schnermann, J., and J. P. Briggs. Interaction between loop of Henle flow and arterial pressure as determinants of glomerular pressure. Am. J. Physiol. 256 (Renal Fluid Electrolyte Physiol. 25): F421–F429, 1989.
 238. Schnermann, J., and J. P. Briggs. Single nephron comparison of the effect of loop of Henle flow on filtration rate and pressure in control and angiotensin II‐infused rats. Miner. Electrolyte Metab. 15: 103–107, 1989.
 239. Schnermann, J., and J. P. Briggs. Restoration of tubuloglomerular feedback in volume expanded rats by angiotensin II. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F565–F572, 1990.
 240. Schnermann, J., J. P. Briggs, W. Kriz, L. Moore, and F. S. Wright. Control of glomerular vascular resistance by the tubuloglomerular feedback mechanism. In: Renal Pathophysiology, edited by A. Leaf, G. Giebisch, L. Bolis, and S. Gorini. New York: Raven, 1980, pp. 165–182.
 241. Schnermann, J., J. P. Briggs, G. Schubert, and M. Marin‐Grez. Opposing effects of captopril and aprotinin on tubuloglomerular feedback responses. Am. J. Physiol. 247 (Renal Fluid Electrolyte Physiol. 16): F912–F918, 1984.
 242. Schnermann, J., J. P. Briggs, and P. C. Weber. Tubuloglomerular feedback, prostaglandins, and angiotensin in the autoregulation of glomerular filtration rate. Kidney Int. 25: 53–64, 1984.
 243. Schnermann, J., J. P. Briggs, and F. S. Wright. Feedback‐mediated reduction of glomerular filtration rate during infusion of hypertonic saline. Kidney Int. 20: 462–468, 1981.
 244. Schnermann, J., J. M. Davis, P. Wunderlich, D. Z. Levine, and M. Horster. Technical problems in the micropuncture determination of nephron filtration rate and their functional implications. Pflugers Arch. 329: 307–320, 1971.
 245. Schnermann, J., M. Gokel, P. C. Weber, G. Schubert, and J. P. Briggs. Tubuloglomerular feedback and glomerular morphology in Goldblatt hypertensive rats on varying protein diets. Kidney Int. 29: 520–529, 1986.
 246. Schnermann, J., and M. Hermle. Maintenance of feedback regulation of filtration dynamics in the absence of divalent cations in the lumen of the distal tubule. Pflugers Arch. 358: 311–323, 1975.
 247. Schnermann, J., M. Hermle, F. Schmidmeier, and H. Dahlheim. Impaired potency for feedback regulation of glomerular filtration rate in DOCA escaped rats. Pflugers Arch. 358: 325–338, 1975.
 248. Schnermann, J., and D. Z. Levine. Tubular control of glomerular filtration rate in single nephrons. Can. J. Physiol. Pharmacol. 53: 325–329, 1975.
 249. Schnermann, J., and D. Marver. ATPase activity in macula densa cells of the rabbit kidney. Pflugers Arch. 407: 82–86, 1986.
 250. Schnermann, J., H. Osswald, and M. Hermle. Inhibitory effect of methylxanthines on feedback control of glomerular filtration rate in the rat kidney. Pflugers Arch. 369: 39–48, 1977.
 251. Schnermann, J., A. E. G. Persson, and B. Agerup. Tubuloglomerular feedback. Non‐linear relationship between glomerular hydrostatic pressure and loop of Henle perfusion rate. J. Clin. Invest. 52: 862–869, 1973.
 252. Schnermann, J., D. W. Ploth, and M. Hermle. Activation of tubulo‐glomerular feedback by chloride transport. Pflugers Arch. 362: 229–240, 1976.
 253. Schnermann, J., G. Schubert, and J. P. Briggs. In situ studies of the distal convoluted tubule in the rat. I. Evidence for NaCl secretion. Am. J. Physiol. 243 (Renal Fluid Electrolyte Physiol. 12): F160–F166, 1982.
 254. Schnermann, J., G. Schubert, and J. P. Briggs. Tubuloglomerular feedback responses with native and artificial tubular fluid. Am. J. Physiol. 250 (Renal Fluid Electrolyte Physiol. 19): F16–F21, 1986.
 255. Schnermann, J., G. Schubert, M. Hermle, R. Herbst, N. T. Stowe, S. Yarimizu, and P. C. Weber. The effect of inhibition of prostaglandin synthesis on tubuloglomerular feedback in the rat kidney. Pflugers Arch. 379: 269–286, 1979.
 256. Schnermann, J., N. T. Stowe, S. Yarimizu, and M. Magnusson. Feedback regulation of glomerular filtration rate in isolated kidneys. Pflugers Arch. 368 (Suppl.): R14, 1977.
 257. Schnermann, J., K. M. Todd, and J. P. Briggs. Effect of dopamine on the tubuloglomerular feedback mechanism. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F790–F798, 1990.
 258. Schnermann, J., and P. C. Weber. Reversal of indomethacin‐induced inhibition of tubuloglomerular feedback by prostaglandin infusion. Prostaglandins 24: 351–361, 1982.
 259. Schnermann, J., H. Weihprecht, and J. P. Briggs. Inhibition of tubuloglomerular feedback during adenosine1‐receptor blockade. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F553–F561, 1990.
 260. Schnermann, J., H. Weihprecht, J. A. Davis, and J. P. Briggs. Inhibition of tubuloglomerular feedback‐ and agonist‐induced vasoconstriction by cyclic AMP. Xlth International Congr. Nephrol. (abstracts), 32A, 1990.
 261. Schnermann, J., F. S. Wright, J. M. Davis, W. v. Stackelberg, and G. Grill. Regulation of superficial nephron filtration rate by tubuloglomerular feedback. Pflugers Arch. 318: 147–175, 1970.
 262. Schwietzer, G., and K. H. Gertz. Changes of hemodynamics and glomerular ultrafiltration in renal hypertension of rats. Kidney Int. 15: 134–143, 1979.
 263. Selén, G., R. Müller‐Suur, and A. E. G. Persson. Activation of the tubuloglomerular feedback mechanism in dehydrated rats. Acta Physiol. Scand. 117: 83–89, 1983.
 264. Selén, G., and A. E. G. Persson. Effects of reduced renal artery pressure on feedback control of glomerular filtrate. Am. J. Physiol. 244 (Renal Fluid Electrolyte Physiol. 13): F342–F348, 1983.
 265. Selén, G., and A. E. G. Persson. Hydrostatic and oncotic pressures in the interstitium of dehydrated and volume expanded rats. Acta Physiol. Scand. 117: 75–81, 1983.
 266. Seney, F. D., A. E. G. Persson, and F. S. Wright. Modification of tubuloglomerular feedback signal by dietary protein. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F83–F90, 1987.
 267. Seney, F. D., and F. S. Wright. Dietary protein suppresses feedback control of glomerular filtration in rats. J. Clin. Invest. 75: 558–568, 1985.
 268. Seney, F. D., and F. S. Wright. Signal for tubuloglomerular feedback control of GFR: separate changes of sodium and chloride at constant osmolality. Kidney Int. 29: 388, 1986.
 269. Skøtt, O. Do osmotic forces play a role in renin secretion? Am. J. Physiol. 255 (Renal Fluid Electrolyte Physiol. 24): F1–F10, 1988.
 270. Skøtt, O., and J. P. Briggs. Direct demonstration of macula densa‐mediated renin secretion. Science 237: 1618–1620, 1987.
 271. Smith, W. L., and T. G. Bell. Immunohistochemical localization of the prostaglandin‐forming cyclooxygenase in renal cortex. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F451–F457, 1978.
 272. Spielman, W. S., and C. I. Thompson. A proposed role for adenosine in the regulation of renal hemodynamics and renin release. Am. J. Physiol. 242 (Renal Fluid Electrolyte Physiol. 11): F423–F435, 1982.
 273. Steinhausen, M., M. Blum, J. T. Fleming, F. G. Holz, N. Parekh, and D. L. Wiegman. Visualization of renal autoreg‐ulation in the split hydronephrotic kidney of rats. Kidney Int. 35: 1151–1160, 1989.
 274. Steinhausen, M., J. T. Fleming, F. G. Holz, and N. Parekh. Nitrendipine and the pressure‐dependent vasodilatation of vessels in the hydronephrotic kidney. J. Cardiovasc. Pharmacol. 9 (Suppl. 1): S39–S43, 1987.
 275. Steinhausen, M., B. Zimmerhacki, H. Thederan, R. Dussel, N. Parekh, H. U. Eßlinger, G. V. Hagens, D. Komitowsky, and F. D. Dallenbach. Intraglomerular microcir‐culation: measurements of single glomerular loop flow in rats. Kidney Int. 20: 230–239, 1981.
 276. Stowe, N. T., J. Schnermann, and M. Hermle. Feedback regulation of nephron filtration rate during pharmacologic interference with the renin‐angiotensin and adrenergic systems in rats. Kidney Int. 15: 473–486, 1979.
 277. Takabatake, T. Feedback regulation of glomerular filtration in the denervated rat kidney. Kidney Int. 22 (Suppl. 12): S129–S135, 1982.
 278. Takabatake, T., Y. Ushiogi, and N. Hattori. Effects of volume replacement on tubuloglomerular feedback activity in spontaneously hypertensive rats. In: The Juxtaglomerular Apparatus and the Tubuloglomerular Feedback Mechanism, edited by A. E. G. Persson and U. Boberg. Amsterdam: Elsevier, 1988, pp. 289–296.
 279. Takabatake, T., Y. Ushiogi, K. Ohta, and N. Hattori. Attenuation of enhanced tubuloglomerular feedback activity in SHR by renal denervation. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F980–F985, 1990.
 280. Tanner, G. A. Effects of kidney tubule obstruction on glomerular function in rats. Am. J. Physiol. 237 (Renal Fluid Electrolyte Physiol. 6): 379–385, 1979.
 281. Tanner, G. A. Nephron obstruction and tubuloglomerular feedback. Kidney Int. 22 (Suppl. 12): S213–S218, 1982.
 282. Tanner, G. A. Tubuloglomerular feedback after nephron or ureteral obstruction. Am. J. Physiol. 248 (Renal Fluid Electrolyte Physiol. 17): F688–F697, 1985.
 283. Taugner, R., and E. Hackenthal. Angiotensin II in epithelioid (renin containing) cells of rat kidney. Histochemistry 72: 499–509, 1981.
 284. Taugner, R., and E. Hackenthal. The Juxtaglomerular Apparatus. Berlin: Springer‐Verlag, 1989.
 285. Thurau, K. Fundamentals of Renal Circulation. Proc. 2nd Int. Congr. Nephrol., Prague; Amsterdam: Excerpta Medica, 1963, pp. 51–61.
 286. Thurau, K. Renal hemodynamics. Am. J. Physiol. 36: 698–719, 1964.
 287. Thurau, K., and J. Mason. The intrarenal function of the juxtaglomerular apparatus. In: MTP Int. Rev. Sci., Kidney and Urinary Tract Physiology, edited by K. Thurau. Baltimore: University Park, Ser. 1, Vol. 6, 1974, pp. 357–389.
 288. Thurau, K., A. Grüner, J. Mason, and H. Dahlheim. Tubular signal for the renin activity in the juxtaglomerular apparatus. Kidney Int. 22 (Suppl. 12): S55–S62, 1982.
 289. Thurau, K., and J. Schnermann. Die Natriumkonzentration an den Macula densa Zellen als regulierender Faktor für das Glomerulumfiltrat (Mikropunktionsversuche). Klin. Wochenschr. 43: 410–413, 1965.
 290. Tucker, B. J., and R. C. Blantz. Effect of furosemide administration on glomerular and tubular dynamics in the rat. Kidney Int. 26: 112–121, 1984.
 291. Tucker, B. J., R. W. Steiner, L. C. Gushwa, and R. C. Blantz. Studies on the tubulo‐glomerular feedback system in the rat. The mechanism of reduction in filtration rate with benzolamide. J. Clin. Invest. 62: 993–1004, 1978.
 292. Vander, A. J. Control of renin release. Physiol. Rev. 47: 359–382, 1967.
 293. Wahlberg, J., A. Stenberg, D. Wilson, and A. E. G. Persson. Tubuloglomerular feedback and interstitial pressure in obstructive nephropathy. Kidney Int. 26: 294–302, 1984.
 294. Welch, W. J., and C. S. Wilcox. Modulating role of thromboxane in the tubuloglomerular feedback response in the rat. J. Clin. Invest. 81: 1843–1849, 1988.
 295. Welch, W. J., and C. S. Wilcox. Feedback responses during sequential inhibition of angiotensin and thromboxane. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F457–F466, 1990.
 296. Welch, W. J., C. S. Wilcox, S. S. Gross, and R. Levi. Involvement of EDRF in tubuloglomerular feedback and intrinsic renal vasoconstriction. FASEB J. 4: A1077, 1990.
 297. Wilcox, C. S. Regulation of renal blood flow by plasma chloride. J. Clin. Invest. 71: 726–735, 1983.
 298. Woods, L. L., H. L. Mizelle, J.‐P. Montani, and J. E. Hall. Mechanisms controlling renal hemodynamics and electrolyte excretion during amino acids. Am. J. Physiol. 251 (Renal Fluid Electrolyte Physiol. 20): F303–F312, 1986.
 299. Woods, L. L., H. L. Mizelle, and J. E. Hall. Control of renal hemodynamics in hyperglycemia: possible role of tubuloglomerular feedback. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F65–F73, 1987.
 300. Wright, F. S., and J. P. Briggs. Feedback regulation of glomerular filtration rate. Am. J. Physiol. 233 (Renal Fluid Electrolyte Physiol. 2): F1–F7, 1977.
 301. Wright, F. S., and J. P. Briggs. Feedback control of glomerular blood flow, pressure and filtration rate. Physiol. Rev. 59: 958–1006, 1979.
 302. Wright, F. S., H. Mandin, and A. E. G. Persson. Studies of the sensing mechanism in the tubuloglomerular feedback pathway. Kidney Int. 22 (Suppl. 12): S90–S96, 1982.
 303. Wright, F. S., and J. Schnermann. Interference with feedback control of glomerular filtration rate by furosemide, triflocin, and cyanide. J. Clin. Invest. 53: 1695–1708, 1974.
 304. Wunderlich, P., F. P. Brunner, J. M. Davis, D. Häberle, H. Thölen, and G. Thiel. Feedback activation in rat neph‐rons by sera from patients with acute renal failure. Kidney Int. 17: 497–506, 1980.
 305. Yip, K.‐P., N.‐H. Holstein‐Rathlou, and D. J. Marsh. Chaotic fluctuations of tubular pressure in spontaneous and Goldblatt hypertension. Kidney Int. 37: 558, 1990.
 306. Zimmerhackl, B., N. Parekh, H. Kücherer, and M. Steinhausen. Influence of systemically applied angiotensin II on the microcirculation of glomerular capillaries in the rat. Kidney Int. 27: 17–24, 1985.
 307. Zimmermann, K. W. Ueber den Bau des Glomerulus der Säugerniere. Z. Mikr. Anat. Forsch. 32: 176–278, 1933.

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Article Title: Tubuloglomerular Feedback Control of Renal Vascular Resistance
 

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Jürgen Schnermann, Dieter A. Häberle, John M. Davis, Klaus Thurau. Tubuloglomerular Feedback Control of Renal Vascular Resistance. Compr Physiol 2011, Supplement 25: Handbook of Physiology, Renal Physiology: 1675-1705. First published in print 1992. doi: 10.1002/cphy.cp080234